Recognition of extended linear and cyclised polyketide mimics by a type II acyl carrier protein† †Electronic supplementary information (ESI) available: Detailed experimental procedures and characterisation data for all new compounds, additional spectra and structural statistics for derivatised ACP three-dimensional structures. See DOI: 10.1039/c5sc03864b Click here for additional data file.

Enantioselective Narasaka–Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters† †Electronic supplementary information (ESI) available: Experimental procedures and characterisation data for all compounds are provided. CCDC 1438659 and 1438660. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc04466b Click here for additional data file. Click here for additional data file.

School of Chemistry, University of Bristol, B bris.ac.uk AstraZeneca, Alderley Park, Maccleseld, C AstraZeneca, Pepparedsleden 1, Mölndal, 4 † Electronic supplementary information ( and characterisation data for all compou 1438660. For ESI and crystallographic dat DOI: 10.1039/c6sc04466b ‡ These authors contributed equally. § Author to whom correspondence shou structures of 3b and Pd[(Sa,S)-L-...

A Lewis acid β-diiminato-zinc-complex as all-rounder for co- and terpolymerisation of various epoxides with carbon dioxide† †Electronic supplementary information (ESI) available: Detailed experimental procedures, GPC data, NMR spectra and crystallographic data. CCDC 1508589–1508590. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc04477h Click here for additional data file. Click here for additional data file.

Substrate selectivity of an isolated enoyl reductase catalytic domain from an iterative highly reducing fungal polyketide synthase reveals key components of programming† †Electronic supplementary information (ESI) available: Details of all experimental and characterisation data. See DOI: 10.1039/c6sc03496a Click here for additional data file. Click here for additional data file. Click here for additional data file.

Highly selective acylation of polyamines and aminoglycosides by 5-acyl-5-phenyl-1,5-dihydro-4H-pyrazol-4-ones† †Electronic supplementary information (ESI) available: Experimental procedures, kinetic data, UV/Vis spectra, NMR spectra, and HPLC traces. X-ray data for 44. CCDC 1563600. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc03184j Click here for additional data file. Click here for additional data file.

Converting disulfide bridges in native peptides to stable methylene thioacetals† †Electronic supplementary information (ESI) available: Experimental procedures and characterisation of all new compounds. See DOI: 10.1039/c6sc02285e Click here for additional data file.